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CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype

BACKGROUND: Platinum resistance is a major challenge in the clinical treatment of advanced ovarian cancer (OC). Accumulating evidence shows that the tumor-promotive M2 macrophage is linked to the limiting chemotherapy efficacy of multiple malignancies including OC. Circular RNAs (circRNAs) are a nov...

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Detalles Bibliográficos
Autores principales: Li, Han, Luo, Fan, Jiang, Xingyu, Zhang, Weijing, Xiang, Tong, Pan, Qiuzhong, Cai, Liming, Zhao, Jingjing, Weng, Desheng, Li, Yue, Dai, Yuhu, Sun, Fengze, Yang, Chaopin, Huang, Yue, Yang, Jieying, Tang, Yan, Han, Yulong, He, Mian, Zhang, Yanna, Song, Libing, Xia, Jian-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919471/
https://www.ncbi.nlm.nih.gov/pubmed/35277458
http://dx.doi.org/10.1136/jitc-2021-004029