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Iron out KRAS-driven cancer

How to specifically target oncogenic KRAS-driven cancers while sparing normal tissues remains an unmet need in cancer therapy. In this issue of JEM, Jiang et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20210739) leveraged KRAS-induced iron addiction in cancer cells to design a clever drug de...

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Detalles Bibliográficos
Autores principales: Lei, Guang, Gan, Boyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919642/
https://www.ncbi.nlm.nih.gov/pubmed/35262627
http://dx.doi.org/10.1084/jem.20212166