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Loss of Slc38a4 imprinting is a major cause of mouse placenta hyperplasia in somatic cell nuclear transferred embryos at late gestation

Placenta hyperplasia is commonly observed in cloned animals and is believed to impede the proper development of cloned embryos. However, the mechanism underlying this phenomenon is largely unknown. Here, we show that placenta hyperplasia of cloned mouse embryos occurs in both middle and late gestati...

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Detalles Bibliográficos
Autores principales: Xie, Zhenfei, Zhang, Wenhao, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8919768/
https://www.ncbi.nlm.nih.gov/pubmed/35196486
http://dx.doi.org/10.1016/j.celrep.2022.110407