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Biomimetic properties and estimated in vivo distribution of chloroquine and hydroxy-chloroquine enantiomers

Chloroquine and hydroxy-chloroquine already established as anti-malarial and lupus drugs have recently gained renewed attention in the fight against the Covid-19 pandemic. Bio-mimetic HPLC methods have been used to measure the protein and phospholipid binding of the racemic mixtures of the drugs. Th...

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Detalles Bibliográficos
Autores principales: Valko, Klara L, Zhang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Association of Physical Chemists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920107/
https://www.ncbi.nlm.nih.gov/pubmed/35299770
http://dx.doi.org/10.5599/admet.929