Potent Inhibition of Human Cytochrome P450 3A4 by Biflavone Components from Ginkgo Biloba and Selaginella Tamariscina

CYP3A4-mediated Phase I biotransformation is the rate-limiting step of elimination for many commonly used clinically agents. The modulatory effects of herbal medicines on CYP3A4 activity are one of the risk factors affecting the safe use of drug and herbal medicine. In the present study, the inhibit...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Shi, Chao, Feng, Lei, Pan, Wei, Tian, Xiang-Ge, Sun, Cheng-Peng, Wang, Chao, Ning, Jing, Lv, Xia, Wang, Yan, Yuan, Qian-Hui, Guan, Rui-Xuan, Zhang, Hou-Li, Ma, Xiao-Chi, Ma, Tong-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920304/
https://www.ncbi.nlm.nih.gov/pubmed/35295338
http://dx.doi.org/10.3389/fphar.2022.856784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920304/
https://www.ncbi.nlm.nih.gov/pubmed/35295338
http://dx.doi.org/10.3389/fphar.2022.856784

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