Design, synthesis and biological evaluation of a series of dianilinopyrimidines as EGFR inhibitors

This paper described our efforts to develop dianilinopyrimidines as novel EGFR inhibitors. All the target compounds were tested for inhibitory effects against wild type EGFR (EGFR(wt)) and three tumour cells, including A549, PC-3, and HepG2. Some of the compounds performed well in antitumor activiti...

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Detalles Bibliográficos
Autores principales: Yan, Longjia, Wang, Qin, Liu, Li, Le, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920385/
https://www.ncbi.nlm.nih.gov/pubmed/35260020
http://dx.doi.org/10.1080/14756366.2022.2046567

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920385/
https://www.ncbi.nlm.nih.gov/pubmed/35260020
http://dx.doi.org/10.1080/14756366.2022.2046567

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