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Epigallocatechin-3-O-gallate promotes extracellular matrix and inhibits inflammation in IL-1β stimulated chondrocytes by the PTEN/miRNA-29b pathway

CONTEXT: Epigallocatechin-3-O-gallate (EGCG) exhibits anti-arthritic activity. MiR-29b-3p provokes chondrocyte apoptosis and promotes the initiation and development of osteoarthritis (OA). OBJECTIVE: To explore the roles of EGCG and miR-29b-3p in interleukin-1β (IL-1β)-stimulated chondrocytes. MATER...

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Detalles Bibliográficos
Autores principales: Yang, Dong, Cao, Guanghua, Ba, Xiaorong, Jiang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920401/
https://www.ncbi.nlm.nih.gov/pubmed/35260041
http://dx.doi.org/10.1080/13880209.2022.2039722