Sorafenib-loaded nanostructured lipid carriers for topical ocular therapy of corneal neovascularization: development, in-vitro and in vivo study

Sorafenib (SRB), a multikinase inhibitor, is effective in reducing experimental corneal neovascularization (CNV) after oral administration; however, its therapeutic use in ocular surface disorders is restricted due to poor solubility and limited bioavailability. This study aimed to develop and optim...

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Detalles Bibliográficos
Autores principales: Luo, Qing, Yang, Jingjing, Xu, Haohang, Shi, Jieran, Liang, Zhen, Zhang, Rui, Lu, Ping, Pu, Guojuan, Zhao, Ningmin, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920403/
https://www.ncbi.nlm.nih.gov/pubmed/35277107
http://dx.doi.org/10.1080/10717544.2022.2048134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920403/
https://www.ncbi.nlm.nih.gov/pubmed/35277107
http://dx.doi.org/10.1080/10717544.2022.2048134

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