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Paired box 5 increases the chemosensitivity of esophageal squamous cell cancer cells by promoting p53 signaling activity

BACKGROUND: Gene promoter methylation is a major epigenetic change in cancers, which plays critical roles in carcinogenesis. As a crucial regulator in the early stages of B-cell differentiation and embryonic neurodevelopment, the paired box 5 (PAX5) gene is downregulated by methylation in several ki...

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Detalles Bibliográficos
Autores principales: Zhang, Weiwei, Yan, Wenji, Qian, Niansong, Han, Quanli, Zhang, Weitao, Dai, Guanghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920431/
https://www.ncbi.nlm.nih.gov/pubmed/35191417
http://dx.doi.org/10.1097/CM9.0000000000002018