Defective dimerization of FoF1‐ATP synthase secondary to glycation favors mitochondrial energy deficiency in cardiomyocytes during aging

Aged cardiomyocytes develop a mismatch between energy demand and supply, the severity of which determines the onset of heart failure, and become prone to undergo cell death. The FoF1‐ATP synthase is the molecular machine that provides >90% of the ATP consumed by healthy cardiomyocytes and is prop...

Descripción completa

Detalles Bibliográficos
Autores principales: Bou‐Teen, Diana, Fernandez‐Sanz, Celia, Miro‐Casas, Elisabet, Nichtova, Zuzana, Bonzon‐Kulichenko, Elena, Casós, Kelly, Inserte, Javier, Rodriguez‐Sinovas, Antonio, Benito, Begoña, Sheu, Shey‐Shing, Vázquez, Jesús, Ferreira‐González, Ignacio, Ruiz‐Meana, Marisol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920436/
https://www.ncbi.nlm.nih.gov/pubmed/35233924
http://dx.doi.org/10.1111/acel.13564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920436/
https://www.ncbi.nlm.nih.gov/pubmed/35233924
http://dx.doi.org/10.1111/acel.13564

Ejemplares similares