Aging alters the metabolic flux signature of the ER‐unfolded protein response in vivo in mice

Age is a risk factor for numerous diseases, including neurodegenerative diseases, cancers, and diabetes. Loss of protein homeostasis is a central hallmark of aging. Activation of the endoplasmic reticulum unfolded protein response (UPR(ER)) includes changes in protein translation and membrane lipid...

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Detalles Bibliográficos
Autores principales: Ward, Catherine P., Peng, Lucy, Yuen, Samuel, Halstead, John, Palacios, Hector, Nyangau, Edna, Mohammed, Hussein, Ziari, Naveed, Dandan, Mohamad, Frakes, Ashley E., Gildea, Holly K., Dillin, Andrew, Hellerstein, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920450/
https://www.ncbi.nlm.nih.gov/pubmed/35170180
http://dx.doi.org/10.1111/acel.13558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920450/
https://www.ncbi.nlm.nih.gov/pubmed/35170180
http://dx.doi.org/10.1111/acel.13558

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