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Epithelial-to-mesenchymal transition proceeds through directional destabilization of multidimensional attractor

How a cell changes from one stable phenotype to another one is a fundamental problem in developmental and cell biology. Mathematically, a stable phenotype corresponds to a stable attractor in a generally multi-dimensional state space, which needs to be destabilized so the cell relaxes to a new attra...

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Detalles Bibliográficos
Autores principales: Wang, Weikang, Poe, Dante, Yang, Yaxuan, Hyatt, Thomas, Xing, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920502/
https://www.ncbi.nlm.nih.gov/pubmed/35188459
http://dx.doi.org/10.7554/eLife.74866