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Prompt Antiviral Action of Pulmonary CD8+ T(RM) Cells Is Mediated by Rapid IFN-γ Induction and Its Downstream ISGs in the Lung
Growing lines of evidence supported the importance of CD8+ lung tissue resident memory T (T(RM)) cells in protection against respiratory viruses, exemplified by influenza A virus. However, the underlying in vivo mechanism remains largely undetermined. Here, we used mouse infection models to dissect...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920550/ https://www.ncbi.nlm.nih.gov/pubmed/35296070 http://dx.doi.org/10.3389/fimmu.2022.839455 |