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DNMT1-Mediated DNA Methylation Targets CDKN2B to Promote the Repair of Retinal Ganglion Cells in Streptozotocin-Induced Mongolian Gerbils during Diabetic Retinopathy

OBJECTIVE: DNA methylation played a vital role in the progression of diabetic retinopathy. In this study, we aimed to explore the role of DNA cytosine-5-methyltransferase 1 (DNMT1) in the development of early diabetic retinopathy and its potential underlying mechanism. METHODS: Eight-week-old health...

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Detalles Bibliográficos
Autores principales: Wang, Xue, Zhang, Jinling, Liao, Yujie, Jin, Yiping, Yu, Xiaoyan, Li, Hong, Yang, Qi, Li, Xiaomei, Chen, Ranran, Wu, Danping, Zhu, Haohao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920618/
https://www.ncbi.nlm.nih.gov/pubmed/35295199
http://dx.doi.org/10.1155/2022/9212116