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Folate Receptor-Alpha Targeted 7x19 CAR-γδT Suppressed Triple-Negative Breast Cancer Xenograft Model in Mice

BACKGROUND: Triple-negative breast cancer (TNBC) is the worst prognosis subtype of breast cancer due to lack of specific targets. Recent studies have shown that immunotherapy may solve that problem by targeting folate receptor-alpha (FRα). METHODS: Gene modified γδ T cells were manufactured to expre...

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Detalles Bibliográficos
Autores principales: Ye, Xueshuai, Deng, Xinna, Wen, Junye, Li, Yang, Zhang, Mengya, Cai, Ziqi, Liu, Guan, Wang, Hezhi, Cai, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920629/
https://www.ncbi.nlm.nih.gov/pubmed/35295709
http://dx.doi.org/10.1155/2022/2112898