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Global profiling of phosphorylation-dependent changes in cysteine reactivity

Proteomics has revealed that the ~20,000 human genes engender a far greater number of proteins, or proteoforms, that are diversified in large part by post-translational modifications (PTMs). How such PTMs affect protein structure and function is an active area of research but remains technically cha...

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Detalles Bibliográficos
Autores principales: Kemper, Esther K., Zhang, Yuanjin, Dix, Melissa M., Cravatt, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920781/
https://www.ncbi.nlm.nih.gov/pubmed/35228727
http://dx.doi.org/10.1038/s41592-022-01398-2