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Transcriptional kinetics and molecular functions of long noncoding RNAs

An increasing number of long noncoding RNAs (lncRNAs) have experimentally confirmed functions, yet little is known about their transcriptional dynamics and it is challenging to determine their regulatory effects. Here, we used allele-sensitive single-cell RNA sequencing to demonstrate that, compared...

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Detalles Bibliográficos
Autores principales: Johnsson, Per, Ziegenhain, Christoph, Hartmanis, Leonard, Hendriks, Gert-Jan, Hagemann-Jensen, Michael, Reinius, Björn, Sandberg, Rickard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920890/
https://www.ncbi.nlm.nih.gov/pubmed/35241826
http://dx.doi.org/10.1038/s41588-022-01014-1