Sequence determinants of human gene regulatory elements

DNA can determine where and when genes are expressed, but the full set of sequence determinants that control gene expression is unknown. Here, we measured the transcriptional activity of DNA sequences that represent an ~100 times larger sequence space than the human genome using massively parallel r...

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Detalles Bibliográficos
Autores principales: Sahu, Biswajyoti, Hartonen, Tuomo, Pihlajamaa, Päivi, Wei, Bei, Dave, Kashyap, Zhu, Fangjie, Kaasinen, Eevi, Lidschreiber, Katja, Lidschreiber, Michael, Daub, Carsten O., Cramer, Patrick, Kivioja, Teemu, Taipale, Jussi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920891/
https://www.ncbi.nlm.nih.gov/pubmed/35190730
http://dx.doi.org/10.1038/s41588-021-01009-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920891/
https://www.ncbi.nlm.nih.gov/pubmed/35190730
http://dx.doi.org/10.1038/s41588-021-01009-4

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