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The Ragulator complex serves as a substrate-specific mTORC1 scaffold in regulating the nuclear translocation of transcription factor EB

The mammalian target of rapamycin complex 1 (mTORC1) signaling pathway is activated by intracellular nutritional sufficiency and extracellular growth signals. It has been reported that mTORC1 acts as a hub that integrates these inputs to orchestrate a number of cellular responses, including translat...

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Detalles Bibliográficos
Autores principales: Kimura, Tetsuya, Hayama, Yoshitomo, Okuzaki, Daisuke, Nada, Shigeyuki, Okada, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920921/
https://www.ncbi.nlm.nih.gov/pubmed/35183507
http://dx.doi.org/10.1016/j.jbc.2022.101744