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Nutrient-responsive O-GlcNAcylation dynamically modulates the secretion of glycan-binding protein galectin 3

Endomembrane glycosylation and cytoplasmic O-GlcNAcylation each play essential roles in nutrient sensing, and characteristic changes in glycan patterns have been described in disease states such as diabetes and cancer. These changes in glycosylation have important functional roles and can drive dise...

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Detalles Bibliográficos
Autores principales: Mathew, Mohit P., Abramowitz, Lara K., Donaldson, Julie G., Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920928/
https://www.ncbi.nlm.nih.gov/pubmed/35183508
http://dx.doi.org/10.1016/j.jbc.2022.101743