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Molecular determinants for the chemical activation of the warmth-sensitive TRPV3 channel by the natural monoterpenoid carvacrol

Transient receptor potential vanilloid 3 (TRPV3), robustly expressed in the skin, is a nonselective calcium-permeable cation channel activated by warm temperature, voltage, and certain chemicals. Natural monoterpenoid carvacrol from plant oregano is a known skin sensitizer or allergen that specifica...

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Detalles Bibliográficos
Autores principales: Niu, Canyang, Sun, Xiaoying, Hu, Fang, Tang, Xiaowen, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920929/
https://www.ncbi.nlm.nih.gov/pubmed/35150742
http://dx.doi.org/10.1016/j.jbc.2022.101706