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Emerging Roles of Aldehyde Dehydrogenase Isoforms in Anti-cancer Therapy Resistance

Aldehyde dehydrogenases (ALDHs) are a family of detoxifying enzymes often upregulated in cancer cells and associated with therapeutic resistance. In humans, the ALDH family comprises 19 isoenzymes active in the majority of mammalian tissues. Each ALDH isoform has a specific differential expression p...

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Detalles Bibliográficos
Autores principales: Zanoni, Michele, Bravaccini, Sara, Fabbri, Francesco, Arienti, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8920988/
https://www.ncbi.nlm.nih.gov/pubmed/35299840
http://dx.doi.org/10.3389/fmed.2022.795762