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eIF3a Regulates Colorectal Cancer Metastasis via Translational Activation of RhoA and Cdc42

Tumor metastasis is the major cause of tumor relapse and cancer-associated mortality in colorectal cancer, leading to poor therapeutic responses and reduced survival. eIF3a was previously described as an oncogene. However, its role in colorectal cancer progression and metastasis has not yet been ful...

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Detalles Bibliográficos
Autores principales: Mei, Chao, Liu, Chong, Gao, Ying, Dai, Wen-Ting, Zhang, Wei, Li, Xi, Liu, Zhao-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921074/
https://www.ncbi.nlm.nih.gov/pubmed/35300416
http://dx.doi.org/10.3389/fcell.2022.794329