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Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function

Following spinal cord injury (SCI), multiple signaling cascades are activated instantaneously in the injured segments of the spinal cord to create a complex and pathogenic microenvironment, making it difficult to treat SCI. Nevertheless, the significance of the integrated stress response (ISR) to th...

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Detalles Bibliográficos
Autores principales: Chang, Lei, Liu, Xiangyang, Chen, Jing, Liu, Hongzhe, Wang, Guoping, Wang, Guohua, Liao, Xiaoyun, Shen, Xiongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921087/
https://www.ncbi.nlm.nih.gov/pubmed/34647267
http://dx.doi.org/10.1007/s12031-021-01920-9