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Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function
Following spinal cord injury (SCI), multiple signaling cascades are activated instantaneously in the injured segments of the spinal cord to create a complex and pathogenic microenvironment, making it difficult to treat SCI. Nevertheless, the significance of the integrated stress response (ISR) to th...
Autores principales: | Chang, Lei, Liu, Xiangyang, Chen, Jing, Liu, Hongzhe, Wang, Guoping, Wang, Guohua, Liao, Xiaoyun, Shen, Xiongjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921087/ https://www.ncbi.nlm.nih.gov/pubmed/34647267 http://dx.doi.org/10.1007/s12031-021-01920-9 |
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