Insights into the identification of a molecular signature for amyotrophic lateral sclerosis exploiting integrated microRNA profiling of iPSC-derived motor neurons and exosomes

Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disorder characterized by progressive degeneration of motor neurons (MNs). Most cases are sporadic, whereas 10% are familial. The pathological mechanisms underlying the disease are partially understood, but it is increasingly being reco...

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Detalles Bibliográficos
Autores principales: Rizzuti, Mafalda, Melzi, Valentina, Gagliardi, Delia, Resnati, Davide, Meneri, Megi, Dioni, Laura, Masrori, Pegah, Hersmus, Nicole, Poesen, Koen, Locatelli, Martina, Biella, Fabio, Silipigni, Rosamaria, Bollati, Valentina, Bresolin, Nereo, Comi, Giacomo Pietro, Van Damme, Philip, Nizzardo, Monica, Corti, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921154/
https://www.ncbi.nlm.nih.gov/pubmed/35286466
http://dx.doi.org/10.1007/s00018-022-04217-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921154/
https://www.ncbi.nlm.nih.gov/pubmed/35286466
http://dx.doi.org/10.1007/s00018-022-04217-1

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