Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury

The cytosolic protein rubicon (RUBCN) has been implicated in the removal of necrotic debris and autoimmunity. However, the role of RUBCN in models of acute kidney injury (AKI), a condition that typically involves necrotic kidney tubules, was not investigated. Here, we demonstrate that RUBCN-deficien...

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Detalles Bibliográficos
Autores principales: Tonnus, Wulf, Locke, Sophie, Meyer, Claudia, Maremonti, Francesca, Eggert, Lena, von Mässenhausen, Anne, Bornstein, Stefan R., Green, Douglas R., Linkermann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921192/
https://www.ncbi.nlm.nih.gov/pubmed/35288534
http://dx.doi.org/10.1038/s41419-022-04682-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921192/
https://www.ncbi.nlm.nih.gov/pubmed/35288534
http://dx.doi.org/10.1038/s41419-022-04682-3

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