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Rubicon-deficiency sensitizes mice to mixed lineage kinase domain-like (MLKL)-mediated kidney ischemia-reperfusion injury
The cytosolic protein rubicon (RUBCN) has been implicated in the removal of necrotic debris and autoimmunity. However, the role of RUBCN in models of acute kidney injury (AKI), a condition that typically involves necrotic kidney tubules, was not investigated. Here, we demonstrate that RUBCN-deficien...
Autores principales: | Tonnus, Wulf, Locke, Sophie, Meyer, Claudia, Maremonti, Francesca, Eggert, Lena, von Mässenhausen, Anne, Bornstein, Stefan R., Green, Douglas R., Linkermann, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921192/ https://www.ncbi.nlm.nih.gov/pubmed/35288534 http://dx.doi.org/10.1038/s41419-022-04682-3 |
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