Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice

Glutaredoxin 2 (Grx2) is a glutathione-dependent oxidoreductase that facilitates glutathionylation/de-glutathionylation of target proteins. The main variants of Grx2 are the mitochondrial Grx2a and the cytosolic Grx2c. The aim of this study was to investigate the specific role of mitochondrial Grx2...

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Detalles Bibliográficos
Autores principales: Scalcon, Valeria, Folda, Alessandra, Lupo, Maria Giovanna, Tonolo, Federica, Pei, Naixuan, Battisti, Ilaria, Ferri, Nicola, Arrigoni, Giorgio, Bindoli, Alberto, Holmgren, Arne, Coppo, Lucia, Rigobello, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921303/
https://www.ncbi.nlm.nih.gov/pubmed/35290904
http://dx.doi.org/10.1016/j.redox.2022.102277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921303/
https://www.ncbi.nlm.nih.gov/pubmed/35290904
http://dx.doi.org/10.1016/j.redox.2022.102277

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