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Poly(rC)-binding protein 1 represses ferritinophagy-mediated ferroptosis in head and neck cancer
A cytosolic iron chaperone poly(rC)-binding protein 1 (PCBP1) is a multifunctional RNA-binding protein involving gene transcription, RNA regulation, and iron loading to ferritins. PCBP1 is also known to repress autophagy, but the role of PCBP1 in ferritinophagy and ferroptosis remains unrevealed. Th...
Autores principales: | Lee, Jaewang, You, Ji Hyeon, Roh, Jong-Lyel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921323/ https://www.ncbi.nlm.nih.gov/pubmed/35290903 http://dx.doi.org/10.1016/j.redox.2022.102276 |
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