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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models

Accumulation of amyloid-β (Aβ) oligomers and phosphorylated Tau aggregates are crucial pathological events or factors that cause progressive neuronal loss, and cognitive impairments in Alzheimer's disease (AD). Current medications for AD have failed to halt, much less reverse this neurodegenera...

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Detalles Bibliográficos
Autores principales: Iyaswamy, Ashok, Wang, Xueli, Krishnamoorthi, Senthilkumar, Kaliamoorthy, Venkatapathy, Sreenivasmurthy, Sravan G., Kumar Durairajan, Siva Sundara, Song, Ju-Xian, Tong, Benjamin Chun-kit, Zhu, Zhou, Su, Cheng-Fu, Liu, Jia, Cheung, King-Ho, Lu, Jia-Hong, Tan, Jie-Qiong, Li, Hung Wing, Wong, Man Shing, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921490/
https://www.ncbi.nlm.nih.gov/pubmed/35286997
http://dx.doi.org/10.1016/j.redox.2022.102280