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Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients
Immune checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed cell death protein ligand 1 (PD-L1) axis have been remarkably successful in inducing tumor remissions in several human cancers, yet a substantial number of patients do not respond to treatment. Because this...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921511/ https://www.ncbi.nlm.nih.gov/pubmed/35289334 http://dx.doi.org/10.1038/s41598-022-08356-0 |