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Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients

Immune checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed cell death protein ligand 1 (PD-L1) axis have been remarkably successful in inducing tumor remissions in several human cancers, yet a substantial number of patients do not respond to treatment. Because this...

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Detalles Bibliográficos
Autores principales: Bruns, Imke B., Beltman, Joost B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921511/
https://www.ncbi.nlm.nih.gov/pubmed/35289334
http://dx.doi.org/10.1038/s41598-022-08356-0