Cargando…
Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients
Immune checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed cell death protein ligand 1 (PD-L1) axis have been remarkably successful in inducing tumor remissions in several human cancers, yet a substantial number of patients do not respond to treatment. Because this...
Autores principales: | Bruns, Imke B., Beltman, Joost B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921511/ https://www.ncbi.nlm.nih.gov/pubmed/35289334 http://dx.doi.org/10.1038/s41598-022-08356-0 |
Ejemplares similares
-
Identification and characterization of novel CD274 (PD‐L1) regulating microRNAs and their functional relevance in melanoma
por: Vaxevanis, Christoforos K., et al.
Publicado: (2022) -
Histopathological and genotypic characterization of metastatic colorectal carcinoma with PD‐L1 (CD274)‐expression: Possible roles of tumour micro environmental factors for CD274 expression
por: Inaguma, Shingo, et al.
Publicado: (2017) -
In silico and in vitro protocols for quantifying gene expression noise modulated by microRNAs
por: Wei, Lei, et al.
Publicado: (2022) -
Cellular Localization and Processing of Primary Transcripts of Exonic MicroRNAs
por: Slezak-Prochazka, Izabella, et al.
Publicado: (2013) -
Association of PIK3CA mutation and PTEN loss with expression of CD274 (PD-L1) in colorectal carcinoma
por: Ugai, Tomotaka, et al.
Publicado: (2021)