Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor

OBJECTIVES: Rheumatoid arthritis (RA) is an autoimmune disease strongly associated with the major histocompatibility complex (MHC) class II allele DRB1*04:01, which encodes a protein that binds self-peptides for presentation to T cells. This study characterises the autoantigen-presenting function of...

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Detalles Bibliográficos
Autores principales: Ge, Changrong, Weisse, Sylvia, Xu, Bingze, Dobritzsch, Doreen, Viljanen, Johan, Kihlberg, Jan, Do, Nhu-Nguyen, Schneider, Nadine, Lanig, Harald, Holmdahl, Rikard, Burkhardt, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Rheumatoid Arthritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921575/
https://www.ncbi.nlm.nih.gov/pubmed/35027402
http://dx.doi.org/10.1136/annrheumdis-2021-220500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921575/
https://www.ncbi.nlm.nih.gov/pubmed/35027402
http://dx.doi.org/10.1136/annrheumdis-2021-220500

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