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Development of novel clinical examination scales for the measurement of disease severity in Creutzfeldt-Jakob disease

OBJECTIVE: To use a robust statistical methodology to develop and validate clinical rating scales quantifying longitudinal motor and cognitive dysfunction in sporadic Creutzfeldt-Jakob disease (sCJD) at the bedside. METHODS: Rasch analysis was used to iteratively construct interval scales measuring...

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Detalles Bibliográficos
Autores principales: Nihat, Akin, Mok, Tze How, Odd, Hans, Thompson, Andrew Geoffrey Bourne, Caine, Diana, McNiven, Kirsty, O'Donnell, Veronica, Tesfamichael, Selam, Rudge, Peter, Collinge, John, Mead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921594/
https://www.ncbi.nlm.nih.gov/pubmed/35022318
http://dx.doi.org/10.1136/jnnp-2021-327722