Predicting protein stability changes upon single-point mutation: a thorough comparison of the available tools on a new dataset

Predicting the difference in thermodynamic stability between protein variants is crucial for protein design and understanding the genotype-phenotype relationships. So far, several computational tools have been created to address this task. Nevertheless, most of them have been trained or optimized on...

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Detalles Bibliográficos
Autores principales: Pancotti, Corrado, Benevenuta, Silvia, Birolo, Giovanni, Alberini, Virginia, Repetto, Valeria, Sanavia, Tiziana, Capriotti, Emidio, Fariselli, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921618/
https://www.ncbi.nlm.nih.gov/pubmed/35021190
http://dx.doi.org/10.1093/bib/bbab555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921618/
https://www.ncbi.nlm.nih.gov/pubmed/35021190
http://dx.doi.org/10.1093/bib/bbab555

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