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Predicting protein stability changes upon single-point mutation: a thorough comparison of the available tools on a new dataset
Predicting the difference in thermodynamic stability between protein variants is crucial for protein design and understanding the genotype-phenotype relationships. So far, several computational tools have been created to address this task. Nevertheless, most of them have been trained or optimized on...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921618/ https://www.ncbi.nlm.nih.gov/pubmed/35021190 http://dx.doi.org/10.1093/bib/bbab555 |