TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences

T-cell receptor (TCR) sequencing has enabled the development of innovative diagnostic tests for cancers, autoimmune diseases and other applications. However, the rarity of many T-cell clonotypes presents a detection challenge, which may lead to misdiagnosis if diagnostically relevant TCRs remain und...

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Detalles Bibliográficos
Autores principales: Dahal-Koirala, Shiva, Balaban, Gabriel, Neumann, Ralf Stefan, Scheffer, Lonneke, Lundin, Knut Erik Aslaksen, Greiff, Victor, Sollid, Ludvig Magne, Qiao, Shuo-Wang, Sandve, Geir Kjetil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Problem Solving Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921636/
https://www.ncbi.nlm.nih.gov/pubmed/35062022
http://dx.doi.org/10.1093/bib/bbab566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921636/
https://www.ncbi.nlm.nih.gov/pubmed/35062022
http://dx.doi.org/10.1093/bib/bbab566

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