IFN-γ-Primed hUCMSCs Significantly Reduced Inflammation via the Foxp3/ROR-γt/STAT3 Signaling Pathway in an Animal Model of Multiple Sclerosis

Our previous study showed that interferon gamma (IFN-γ) might enhance the immunosuppressive properties of mesenchymal stem cells (MSCs) by upregulating the expression of indoleamine 2,3-dioxygenease. Therefore, we treated experimental autoimmune encephalomyelitis (EAE) mice, an animal model of multi...

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Detalles Bibliográficos
Autores principales: Ling, Xiao, Wang, Teng, Han, Chao, Wang, Pin, Liu, Xiaoli, Zheng, Chengyun, Bi, Jianzhong, Zhou, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921983/
https://www.ncbi.nlm.nih.gov/pubmed/35300342
http://dx.doi.org/10.3389/fimmu.2022.835345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921983/
https://www.ncbi.nlm.nih.gov/pubmed/35300342
http://dx.doi.org/10.3389/fimmu.2022.835345

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