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The Chaperone Protein GRP78 Promotes Survival and Migration of Head and Neck Cancer After Direct Radiation Exposure and Extracellular Vesicle-Transfer

BACKGROUND AND PURPOSE: Increased levels of the chaperone protein GRP78 have been implicated in poorer outcomes of cancer therapy. We have therefore explored the functional connection between the expression of GRP78 and the development of radioresistance and metastatic behavior in HNSCC. MATERIAL AN...

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Detalles Bibliográficos
Autores principales: Schneider, Michael, Winkler, Klaudia, Kell, Rosemarie, Pfaffl, Michael W., Atkinson, Michael J., Moertl, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8921984/
https://www.ncbi.nlm.nih.gov/pubmed/35299733
http://dx.doi.org/10.3389/fonc.2022.842418