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PKCε Activation Restores Loss of PKCε, Manganese Superoxide Dismutase, Vascular Endothelial Growth Factor, and Microvessels in Aged and Alzheimer’s Disease Hippocampus

Vascular endothelial dysfunction and capillary loss are currently considered to be a primary phenotype of normal human aging and Alzheimer’s disease (AD). Activation of protein kinase C (PKCε) improves several molecular, cellular, physiological, and behavioral endpoints, yet it is not known whether...

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Detalles Bibliográficos
Autores principales: Millien, Guetchyn, Wang, Huaixing, Zhang, Zongxiu, Alkon, Dan L., Hongpaisan, Jarin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922019/
https://www.ncbi.nlm.nih.gov/pubmed/35299945
http://dx.doi.org/10.3389/fnagi.2022.836634