Novel preclinical model for CDKL5 deficiency disorder

Cyclin-dependent kinase-like-5 (CDKL5) deficiency disorder (CDD) is a severe X-linked neurodegenerative disease characterised by early-onset epileptic seizures, low muscle tone, progressive intellectual disability and severe motor function. CDD affects ∼1 in 60,000 live births, with many patients ex...

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Detalles Bibliográficos
Autores principales: Serrano, Rita J., Lee, Clara, Douek, Alon M., Kaslin, Jan, Bryson-Richardson, Robert J., Sztal, Tamar E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922025/
https://www.ncbi.nlm.nih.gov/pubmed/34913468
http://dx.doi.org/10.1242/dmm.049094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922025/
https://www.ncbi.nlm.nih.gov/pubmed/34913468
http://dx.doi.org/10.1242/dmm.049094

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