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Novel preclinical model for CDKL5 deficiency disorder
Cyclin-dependent kinase-like-5 (CDKL5) deficiency disorder (CDD) is a severe X-linked neurodegenerative disease characterised by early-onset epileptic seizures, low muscle tone, progressive intellectual disability and severe motor function. CDD affects ∼1 in 60,000 live births, with many patients ex...
Autores principales: | Serrano, Rita J., Lee, Clara, Douek, Alon M., Kaslin, Jan, Bryson-Richardson, Robert J., Sztal, Tamar E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922025/ https://www.ncbi.nlm.nih.gov/pubmed/34913468 http://dx.doi.org/10.1242/dmm.049094 |
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