A Selective Small‐Molecule c‐Myc Degrader Potently Regresses Lethal c‐Myc Overexpressing Tumors

MYC oncogene is involved in the majority of human cancers and is often associated with poor outcomes, rendering it an extraordinarily desirable target, but therapeutic targeting of c‐Myc protein has been a challenge for >30 years. Here, WBC100, a novel oral active molecule glue that selectively d...

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Detalles Bibliográficos
Autores principales: Xu, Ying, Yu, Qingfeng, Wang, Ping, Wu, Zhaoxing, Zhang, Lei, Wu, Shuigao, Li, Mengyuan, Wu, Bowen, Li, Hongzhi, Zhuang, Haifeng, Zhang, Xuzhao, Huang, Yu, Gan, Xiaoxian, Xu, Rongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922104/
https://www.ncbi.nlm.nih.gov/pubmed/35048559
http://dx.doi.org/10.1002/advs.202104344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922104/
https://www.ncbi.nlm.nih.gov/pubmed/35048559
http://dx.doi.org/10.1002/advs.202104344

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