A systematic review of studies investigating the acute effects of N-methyl- D -aspartate receptor antagonists on behavioural despair in normal animals suggests poor predictive validity

The ability of the N-methyl- D -aspartate receptor antagonist ketamine to induce a rapid and sustained antidepressant effect has led to a surge in pre-clinical studies investigating underlying mechanisms and seeking novel treatments. Animal models are key to this research as they can provide a behav...

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Detalles Bibliográficos
Autores principales: Viktorov, Martin, Wilkinson, Matthew P., Elston, Victoria C. E., Stone, Medi, Robinson, Emma S. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Ketamine and fast acting anti-depressants
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922211/
https://www.ncbi.nlm.nih.gov/pubmed/35299619
http://dx.doi.org/10.1177/23982128221081645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922211/
https://www.ncbi.nlm.nih.gov/pubmed/35299619
http://dx.doi.org/10.1177/23982128221081645

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