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A systematic review of studies investigating the acute effects of N-methyl- D -aspartate receptor antagonists on behavioural despair in normal animals suggests poor predictive validity
The ability of the N-methyl- D -aspartate receptor antagonist ketamine to induce a rapid and sustained antidepressant effect has led to a surge in pre-clinical studies investigating underlying mechanisms and seeking novel treatments. Animal models are key to this research as they can provide a behav...
Autores principales: | Viktorov, Martin, Wilkinson, Matthew P., Elston, Victoria C. E., Stone, Medi, Robinson, Emma S. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922211/ https://www.ncbi.nlm.nih.gov/pubmed/35299619 http://dx.doi.org/10.1177/23982128221081645 |
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