AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus

Interferon regulatory factor 3 (IRF3)‐induced type I interferon (I‐IFN) production plays key roles in both antiviral and autoimmune responses. IRF3 phosphorylation, dimerization, and nuclear localization are needed for its activation and function, but the precise regulatory mechanisms remain to be e...

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Detalles Bibliográficos
Autores principales: Zheng, Xin, Xiao, Jun, Jiang, Qi, Zheng, Lingming, Liu, Chang, Dong, Chen, Zheng, Yuxiao, Ni, Peili, Zhang, Chi, Zhang, Fang, Zhong, Ruiyue, Ding, Huihua, Wang, Qiong, Qiu, Ying, Gao, Minxia, Ding, Jianping, Shen, Nan, Wei, Bin, Wang, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922272/
https://www.ncbi.nlm.nih.gov/pubmed/35191555
http://dx.doi.org/10.15252/embj.2021108016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922272/
https://www.ncbi.nlm.nih.gov/pubmed/35191555
http://dx.doi.org/10.15252/embj.2021108016

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