Increased eEF2K Promotes Glycolysis and Aggressive Behaviors of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis

OBJECTIVE: Aggressive phenotype and abnormal glycolytic metabolism of fibroblast-like synoviocytes (FLSs) are essential to joint inflammation and damage in rheumatoid arthritis (RA). Eukaryotic elongation factor-2 kinase (eEF2K) is a negative regulator of protein synthesis and has been shown to play...

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Detalles Bibliográficos
Autores principales: Chen, Dongying, Cai, Xiaoyan, Ouyang, Hui, Yuan, Shiwen, Wang, Xiaodong, Lin, Lian, Chen, Zhiqing, Huang, Mingcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922331/
https://www.ncbi.nlm.nih.gov/pubmed/35300214
http://dx.doi.org/10.2147/JIR.S337620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922331/
https://www.ncbi.nlm.nih.gov/pubmed/35300214
http://dx.doi.org/10.2147/JIR.S337620

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