ELECTRA-DTA: a new compound-protein binding affinity prediction model based on the contextualized sequence encoding

MOTIVATION: Drug-target binding affinity (DTA) reflects the strength of the drug-target interaction; therefore, predicting the DTA can considerably benefit drug discovery by narrowing the search space and pruning drug-target (DT) pairs with low binding affinity scores. Representation learning using...

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Detalles Bibliográficos
Autores principales: Wang, Junjie, Wen, NaiFeng, Wang, Chunyu, Zhao, Lingling, Cheng, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922401/
https://www.ncbi.nlm.nih.gov/pubmed/35292100
http://dx.doi.org/10.1186/s13321-022-00591-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922401/
https://www.ncbi.nlm.nih.gov/pubmed/35292100
http://dx.doi.org/10.1186/s13321-022-00591-x

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